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 | Acceso al texto completo restringido a Biblioteca INIA La Estanzuela. Por información adicional contacte bib_le@inia.org.uy. |
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Registro completo
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Biblioteca (s) : |
INIA La Estanzuela. |
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Fecha : |
28/09/2020 |
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Actualizado : |
28/09/2020 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Autor : |
SILVA, R.P.; ESPIGOLAN, R.; BERTON, M.P.; STAFUZZA, N.B.; SANTOS, F.S.; NEGREIROS, M.P.; SCHUCHMANN, R.K.; RODRIGUEZ, J.D.; LÔBO, R.B.; BANCHERO, G.; PEREIRA, A.S.C.; BERGMANN, J.A.G.; BALDI, F. |
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Afiliación : |
ROSIANE P. SILVA, Department of Veterinary Medicine, College of Animal Science and Food Engineer, University of São Paulo (USP), 225 Duque de Caxias Norte Avenue, Jardim Elite, 13635-900, Pirassununga/SP, Brazil.; RAFAEL ESPIGOLAN, Department of Veterinary Medicine, College of Animal Science and Food Engineer, University of São Paulo (USP), 225 Duque de Caxias Norte Avenue, Jardim Elite, 13635-900, Pirassununga/SP, Brazil.; MARIANA PIATTO BERTON, Department of Animal Science, College of Agricultural and Veterinarian Sciences, São Paulo State University (UNESP), Via de Acesso Professor Paulo Donato Castellane s/n, 14884-900, Jaboticabal/SP, Brazil.; NEDENIA STAFUZZA, Department of Animal Science, College of Agricultural and Veterinarian Sciences, São Paulo State University (UNESP), Via de Acesso Professor Paulo Donato Castellane s/n, 14884-900, Jaboticabal/SP, Brazil.; F. S. SANTOS, Department of Veterinary Medicine, College of Animal Science and Food Engineer, University of São Paulo (USP), 225 Duque de Caxias Norte Avenue, Jardim Elite, 13635-900, Pirassununga/SP, Brazil.; Department of Veterinary Medicine, College of Animal Science and Food Engineer, University of São Paulo (USP), 225 Duque de Caxias Norte Avenue, Jardim Elite, 13635-900, Pirassununga/SP, Brazil.; Department of Animal Science, College of Agricultural and Veterinarian Sciences, São Paulo State University (UNESP), Via de Acesso Professor Paulo Donato Castellane s/n, 14884-900, Jaboticabal/SP, Brazil.; Department of Animal Science, College of Agricultural and Veterinarian Sciences, São Paulo State University (UNESP), Via de Acesso Professor Paulo Donato Castellane s/n, 14884-900, Jaboticabal/SP, Brazil.; RAYSILDO B. LÔBO, Nacional Association of Breeders and Researchers (ANCP), 463 João Godoy Street, Jardim América, 14020-230, Ribeirão Preto/SP, Brazil.; GEORGGET ELIZABETH BANCHERO HUNZIKER, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; ANGÉLICA SIMONE CRAVO PEREIRA, Department of Veterinary Medicine, College of Animal Science and Food Engineer, University of São Paulo (USP), 225 Duque de Caxias Norte Avenue, Jardim Elite, 13635-900, Pirassununga/SP, Brazil.; JOSÉ AURÉLIO GARCIA BERGMANN, Department of Animal Science, Minas Gerais Federal University (UFMG), Escola de Veterinária da UFMG, Pampulha, 31270-901, Caixa Postal 567, Belo Horizonte/MG, Brazil.; FERNANDO BALDI, Department of Animal Science, College of Agricultural and Veterinarian Sciences, São Paulo State University (UNESP), Via de Acesso Professor Paulo Donato Castellane s/n, 14884-900, Jaboticabal/SP, Brazil. |
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Título : |
Genetic parameters and genomic regions associated with calving ease in primiparous Nellore heifers. |
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Fecha de publicación : |
2020 |
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Fuente / Imprenta : |
Livestock Science, October 2020, Volume 240, Article number 104183. Doi: https://doi.org/10.1016/j.livsci.2020.104183 |
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DOI : |
10.1016/j.livsci.2020.104183 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received 19 February 2020 /Received in revised form 25 June 2020 /Accepted 1 August 2020/Available online 02 August 2020. /Corresponding author: E-mail address: fernandobaldiuy@gmail.com (F. Baldi). This work was supported by the São Paulo Research Foundation -
FAPESP through grant #2018/18921-9, grant #2017/10493-5 and grant #2019/10438-0 for authors Rafael Espigolan, Mariana P. Berton
and Nedenia B. Stafuzza, respectively. |
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Contenido : |
ABSTRACT: The aim of this study was to estimate genetic parameters and to identify genomic regions associated with the calving ease (CE) in precocious Nellore heifers. A total of 1,277 CE phenotypes were collected and scored into two categories: i- non assisted calving, categorized as success (1) and ii- assisted calving where heifers required any form of assistance or intervention to give birth, categorized as failure (2). A pedigree structure containing the identification of the animal's sire and dam was used, with the relationship matrix comprising a total of 6,511
animals. Genotypic data from 1,201 animals were obtained using low-density panel (Clarifide Nelore 3.1) encompassing over 29,001 single nucleotide polymorphisms (SNP) markers. A threshold sire-maternal grandsire model (S-MGS) was used to estimate the genetic parameters, which included sire, maternal grandsire and residual effects as random effects and the fixed effects of contemporary groups (farm and year of calving, sex) and birth weight of the calf as covariable (linear effect). Genomic breeding values were estimated using an animal model with the direct and maternal genetic variances which were previously obtained by means of a S-MGS threshold model. The direct and maternal heritability estimates for CE were obtained considering the covariance of direct and maternal effects fixed as zero. Regions that accounted for more than 0.5% of the additive genetic variance were used. The direct and maternal heritability estimates for CE were low (0.18) and moderate (0.39)
respectively, indicating that genetic progress for this trait is feasible, and so, it would respond favorably to direct selection. Genes identified within the significant windows, such as CA8, FAM110B, TOX, ARID1A, RBM15, HSF1 and PLAG1 were found to be related with maternal and direct effects on CE. Gene enrichment analysis revealed processes that might directly influence fetal processes involved in female pregnancy and stress response. These results should help to better understand the genetic and physiological mechanisms regulating placenta development and fetal development, and this information might be useful for future genomic studies in Nellore cattle. MenosABSTRACT: The aim of this study was to estimate genetic parameters and to identify genomic regions associated with the calving ease (CE) in precocious Nellore heifers. A total of 1,277 CE phenotypes were collected and scored into two categories: i- non assisted calving, categorized as success (1) and ii- assisted calving where heifers required any form of assistance or intervention to give birth, categorized as failure (2). A pedigree structure containing the identification of the animal's sire and dam was used, with the relationship matrix comprising a total of 6,511
animals. Genotypic data from 1,201 animals were obtained using low-density panel (Clarifide Nelore 3.1) encompassing over 29,001 single nucleotide polymorphisms (SNP) markers. A threshold sire-maternal grandsire model (S-MGS) was used to estimate the genetic parameters, which included sire, maternal grandsire and residual effects as random effects and the fixed effects of contemporary groups (farm and year of calving, sex) and birth weight of the calf as covariable (linear effect). Genomic breeding values were estimated using an animal model with the direct and maternal genetic variances which were previously obtained by means of a S-MGS threshold model. The direct and maternal heritability estimates for CE were obtained considering the covariance of direct and maternal effects fixed as zero. Regions that accounted for more than 0.5% of the additive genetic variance were used. The direct and maternal heritabili... Presentar Todo |
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Palabras claves : |
BEEF CATTLE; CANDIDATE GENES; DISTOCIA; FUNCTIONAL ANALYSES; REPRODUCTION TRAITS. |
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Thesagro : |
GANADO VACUNO. |
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Asunto categoría : |
L01 Ganadería |
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Marc : |
LEADER 03747naa a2200361 a 4500
001 1061351
005 2020-09-28
008 2020 bl uuuu u00u1 u #d
024 7 $a10.1016/j.livsci.2020.104183$2DOI
100 1 $aSILVA, R.P.
245 $aGenetic parameters and genomic regions associated with calving ease in primiparous Nellore heifers.$h[electronic resource]
260 $c2020
500 $aArticle history: Received 19 February 2020 /Received in revised form 25 June 2020 /Accepted 1 August 2020/Available online 02 August 2020. /Corresponding author: E-mail address: fernandobaldiuy@gmail.com (F. Baldi). This work was supported by the São Paulo Research Foundation - FAPESP through grant #2018/18921-9, grant #2017/10493-5 and grant #2019/10438-0 for authors Rafael Espigolan, Mariana P. Berton and Nedenia B. Stafuzza, respectively.
520 $aABSTRACT: The aim of this study was to estimate genetic parameters and to identify genomic regions associated with the calving ease (CE) in precocious Nellore heifers. A total of 1,277 CE phenotypes were collected and scored into two categories: i- non assisted calving, categorized as success (1) and ii- assisted calving where heifers required any form of assistance or intervention to give birth, categorized as failure (2). A pedigree structure containing the identification of the animal's sire and dam was used, with the relationship matrix comprising a total of 6,511 animals. Genotypic data from 1,201 animals were obtained using low-density panel (Clarifide Nelore 3.1) encompassing over 29,001 single nucleotide polymorphisms (SNP) markers. A threshold sire-maternal grandsire model (S-MGS) was used to estimate the genetic parameters, which included sire, maternal grandsire and residual effects as random effects and the fixed effects of contemporary groups (farm and year of calving, sex) and birth weight of the calf as covariable (linear effect). Genomic breeding values were estimated using an animal model with the direct and maternal genetic variances which were previously obtained by means of a S-MGS threshold model. The direct and maternal heritability estimates for CE were obtained considering the covariance of direct and maternal effects fixed as zero. Regions that accounted for more than 0.5% of the additive genetic variance were used. The direct and maternal heritability estimates for CE were low (0.18) and moderate (0.39) respectively, indicating that genetic progress for this trait is feasible, and so, it would respond favorably to direct selection. Genes identified within the significant windows, such as CA8, FAM110B, TOX, ARID1A, RBM15, HSF1 and PLAG1 were found to be related with maternal and direct effects on CE. Gene enrichment analysis revealed processes that might directly influence fetal processes involved in female pregnancy and stress response. These results should help to better understand the genetic and physiological mechanisms regulating placenta development and fetal development, and this information might be useful for future genomic studies in Nellore cattle.
650 $aGANADO VACUNO
653 $aBEEF CATTLE
653 $aCANDIDATE GENES
653 $aDISTOCIA
653 $aFUNCTIONAL ANALYSES
653 $aREPRODUCTION TRAITS
700 1 $aESPIGOLAN, R.
700 1 $aBERTON, M.P.
700 1 $aSTAFUZZA, N.B.
700 1 $aSANTOS, F.S.
700 1 $aNEGREIROS, M.P.
700 1 $aSCHUCHMANN, R.K.
700 1 $aRODRIGUEZ, J.D.
700 1 $aLÔBO, R.B.
700 1 $aBANCHERO, G.
700 1 $aPEREIRA, A.S.C.
700 1 $aBERGMANN, J.A.G.
700 1 $aBALDI, F.
773 $tLivestock Science, October 2020, Volume 240, Article number 104183. Doi: https://doi.org/10.1016/j.livsci.2020.104183
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Registro original : |
INIA La Estanzuela (LE) |
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Registro completo
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Biblioteca (s) : |
INIA Tacuarembó. |
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Fecha actual : |
21/02/2014 |
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Actualizado : |
22/02/2014 |
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Autor : |
Fassola, H.E.; Ferrere, P.; Lacorte, S.M.; Rodríguez A., F. |
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Título : |
Predicción de la producción de un pastizal bajo distintas estructuras de canopia de Pinus taeda L. en el noreste de Corrientes, Argentina |
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Fecha de publicación : |
2002 |
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Fuente / Imprenta : |
RIA Revista de Investigaciones Agropecuarias, 2002, v. 31, no. 2, p. 73-95 |
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ISSN : |
0325-8718 |
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Idioma : |
Español |
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Thesagro : |
ARGENTINA; PINUS TAEDA; SISTEMAS SILVOPASCICOLAS. |
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Asunto categoría : |
-- |
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Marc : |
LEADER 00634naa a2200193 a 4500
001 1027561
005 2014-02-22
008 2002 bl uuuu u00u1 u #d
022 $a 0325-8718
100 1 $aFASSOLA, H.E.
245 $aPredicción de la producción de un pastizal bajo distintas estructuras de canopia de Pinus taeda L. en el noreste de Corrientes, Argentina
260 $c2002
650 $aARGENTINA
650 $aPINUS TAEDA
650 $aSISTEMAS SILVOPASCICOLAS
700 1 $aFERRERE, P.
700 1 $aLACORTE, S.M.
700 1 $aRODRÍGUEZ A., F.
773 $tRIA Revista de Investigaciones Agropecuarias, 2002$gv. 31, no. 2, p. 73-95
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INIA Tacuarembó (TBO) |
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